3VQ1
Crystal structure of mouse TLR4/MD-2/lipid IVa complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Toll-like receptor 4 | polymer | 606 | 68713.3 | 2 | UniProt (Q9QUK6) Pfam (PF13855) In PDB | Mus musculus (mouse) | TLR4 |
| 2 | C, D | Lymphocyte antigen 96 | polymer | 144 | 16627.9 | 2 | UniProt (Q9JHF9) In PDB | Mus musculus (mouse) | Ly-96, ESOP-1, Protein MD-2 |
| 3 | E, F, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | C, D | 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose | non-polymer | 711.9 | 2 | Chemie (LP4) | |||
| 6 | C, D | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE | non-polymer | 711.9 | 2 | Chemie (LP5) | |||
| 7 | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170682.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3289.9 | |
| All* | Total formula weight | 175245.5 |
