3VPM
Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribonucleoside-diphosphate reductase subunit M2 | polymer | 286 | 33561.7 | 2 | UniProt (P31350) Pfam (PF00268) | Homo sapiens (human) | Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, F (A, B) | FE (III) ION | non-polymer | 55.8 | 2 | Chemie (FE) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B: 66 - 350 (UniProt: P31350)
| PDB | External Database | Details |
|---|---|---|
| Met 65 | - | expression tag |
| Ala 106 | Glu 106 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67123.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 67283.7 |
