3VP3
Crystal structure of human glutaminase in complex with inhibitor 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutaminase kidney isoform, mitochondrial | polymer | 315 | 34688.6 | 1 | UniProt (O94925) Pfam (PF04960) | Homo sapiens (human) | GLS, K-glutaminase, L-glutamine amidohydrolase |
| 2 | B (A) | 5,5'-pentane-1,5-diylbis(1,3,4-thiadiazol-2-amine) | non-polymer | 270.4 | 1 | Chemie (BP8) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 221 - 533 (UniProt: O94925)
| PDB | External Database | Details |
|---|---|---|
| Ser 219 | - | expression tag |
| Met 220 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34688.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 366.4 | |
| All* | Total formula weight | 35055.1 |
