3VNG

Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Kelch-like ECH-associated protein 1	polymer	309	33825.7	1	UniProt (Q14145) Pfam (PF01344)	Homo sapiens (human)	Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19
2	B (A)	2-(3-((3-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)ureido)methyl)phenoxy)acetic acid	non-polymer		358.3	1	Chemie (FUU)
3	C (A)	water	water		18.0	407	Chemie (HOH)

Sequence modifications

A: 0 - 288 (UniProt: Q14145)

PDB	External Database	Details
Gly -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Leu -8	-	expression tag
Val -7	-	expression tag
Pro -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33825.7
Non-Polymers*	Number of molecules	1
	Total formula weight	358.3
All*	Total formula weight	34184.0

*Water molecules are not included.