3VKM
Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-8 | polymer | 291 | 33110.1 | 2 | UniProt (O00214) Pfam (PF00337) | Homo sapiens (human) | Gal-8, Po66 carbohydrate-binding protein, Po66-CBP, Prostate carcinoma tumor antigen 1, PCTA-1 |
| 2 | C, E (C, E) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 633.6 | 2 | In PDB GlyTouCan (G91237TK) | |||
| 3 | D, F (D, F) | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 2 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 4 | AA, BA, CA, DA, G... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 24 | Chemie (EDO) | |||
| 5 | EA, FA (A, B) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 155 (UniProt: O00214)
A, B: 184 - 317 (UniProt: O00214)
A, B: 184 - 317 (UniProt: O00214)
| PDB | External Database | Details |
|---|---|---|
| His 156 | - | linker |
| Met 157 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66220.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1951.7 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 1489.6 | |
| All* | Total formula weight | 69661.6 |
