3VKE
Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Poly(rC)-binding protein 1 | polymer | 76 | 8462.8 | 4 | UniProt (Q15365) Pfam (PF00013) In PDB | Homo sapiens (human) | Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, hnRNP E1, Nucleic acid-binding protein SUB2.3 |
| 2 | R, S, T, U | DNA (5'-D(P*AP*CP*CP*CP*CP*A)-3') | polymer | 6 | 1738.2 | 4 | |||
| 3 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 14 - 86 (UniProt: Q15365)
| PDB | External Database | Details |
|---|---|---|
| His 12 | - | expression tag |
| Met 13 | - | expression tag |
| Ser 54 | Cys 54 | engineered mutation |
| Trp 87 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 40803.9 | |
| All* | Total formula weight | 40803.9 |
