3VHE
Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vascular endothelial growth factor receptor 2 | polymer | 359 | 40845.9 | 1 | UniProt (P35968) Pfam (PF07714) | Homo sapiens (human) | VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1 |
| 2 | B (A) | 1-{2-fluoro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-(trifluoromethyl)phenyl]urea | non-polymer | 445.4 | 1 | Chemie (42Q) | |||
| 3 | C (A) | water | water | 18.0 | 467 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40845.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 445.4 | |
| All* | Total formula weight | 41291.3 |
