3VHD
Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor, CH5164840
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Heat shock protein HSP 90-alpha | polymer | 229 | 25788.0 | 2 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (human) | Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38 |
| 2 | A, B | 4-amino-18,20-dimethyl-7-thia-3,5,11,15-tetraazatricyclo[15.3.1.1(2,6)]docosa-1(20),2,4,6(22),17(21),18-hexaene-10,16-dione | non-polymer | 385.5 | 2 | Chemie (VHE) | |||
| 3 | water | water | 18.0 | 620 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 236 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| Met 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51575.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 771.0 | |
| All* | Total formula weight | 52346.9 |
