3V97

Crystal structure of bifunctional methyltransferase YcbY (RlmLK) from Escherichia coli, SAH binding

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ribosomal RNA large subunit methyltransferase L	polymer	703	79032.1	2	UniProt (P75864) Pfam (PF22020) Pfam (PF02926) Pfam (PF01170) Pfam (PF10672)	Escherichia coli	rlmLK, 23S rRNA m2G2445 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmL
2	C, D (C, D)	6-O-octanoyl-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose	branched		468.5	2	In PDB BIRD (PRD_900045)		octanoyl-sucrose, esterificated at fructose C6
3	E, F, I, J (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	4	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	G, H, K, L (A, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL) PubChem (753)
5	M, N (A, B)	water	water		18.0	471	Chemie (HOH)

Sequence modifications

A, B: 1 - 702 (UniProt: P75864)

PDB	External Database	Details
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	158064.2
Branched	Number of molecules	2
	Total formula weight	937.0
Non-Polymers*	Number of molecules	8
	Total formula weight	1906.0
All*	Total formula weight	160907.2

*Water molecules are not included.