3V6E
Crystal Structure of USP2 and a mutant form of Ubiquitin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin carboxyl-terminal hydrolase 2 | polymer | 367 | 42171.7 | 1 | UniProt (O75604) Pfam (PF00443) | Homo sapiens (human) | 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin thiolesterase 2, Ubiquitin-specific-processing protease 2 |
| 2 | B (B) | Ubiquitin | polymer | 91 | 10343.8 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 258 - 605 (UniProt: O75604)
B: -2 - 74 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Met 239 | - | expression tag |
| Gly 240 | - | expression tag |
| Ser 241 | - | expression tag |
| Ser 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
| His 245 | - | expression tag |
| His 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
| Ser 249 | - | expression tag |
| Ser 250 | - | expression tag |
| Gly 251 | - | expression tag |
| Leu 252 | - | expression tag |
| Val 253 | - | expression tag |
| Pro 254 | - | expression tag |
| Arg 255 | - | expression tag |
| Gly 256 | - | expression tag |
| Ser 257 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -16 | - | expression tag |
| Ala -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Ser 0 | Gly 76 | engineered mutation |
| Asn 6 | Lys 82 | engineered mutation |
| Ser 9 | Thr 85 | engineered mutation |
| His 12 | Thr 88 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52515.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 228.4 | |
| All* | Total formula weight | 52743.9 |
