3V3N
Crystal structure of TetX2 T280A: an adaptive mutant in complex with minocycline
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | TetX2 protein | polymer | 378 | 42502.1 | 4 | UniProt (Q93L51) Pfam (PF01494) | Bacteroides thetaiotaomicron | |
| 2 | E, I, M, Q (A, B, C, D) | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE | non-polymer | 457.5 | 4 | Chemie (MIY) | |||
| 3 | F, G, J, K, N... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 4 | H, L, P, T (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 5 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 11 - 388 (UniProt: Q93L51)
| PDB | External Database | Details |
|---|---|---|
| Lys 94 | Glu 94 | engineered mutation |
| Lys 266 | Glu 266 | engineered mutation |
| Ala 280 | Thr 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170008.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 5740.6 | |
| All* | Total formula weight | 175749.2 |
