3UYP

Crystal structure of the dengue virus serotype 4 envelope protein domain III in complex with the variable domains of Mab 4E11

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	anti-dengue Mab 4E11	polymer	253	27246.2	1		Mus musculus (mouse)
2	B	Envelope protein	polymer	114	12570.3	1	UniProt (Q9IZJ0) Pfam (PF02832) UniProt (by SIFTS) (Q2YHF0) In PDB	Dengue virus 4
3	A	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
4	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	B	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
6		water	water		18.0	277	Chemie (HOH)

Sequence modifications

B: 296 - 400 (UniProt: Q9IZJ0)

PDB	External Database	Details
Met 295	-	initiating methionine
Leu 401	-	expression tag
Glu 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	39816.5
Non-Polymers*	Number of molecules	8
	Total formula weight	770.8
All*	Total formula weight	40587.3

*Water molecules are not included.