3UY9
Bovine trypsin variant X(tripleGlu217Phe227) in complex with small molecule inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Cationic trypsin | polymer | 223 | 23480.5 | 16 | UniProt (P00760) Pfam (PF00089) In PDB | Bos taurus (bovine) | Beta-trypsin, Alpha-trypsin chain 1, Alpha-trypsin chain 2 |
2 | F, G, H, I, J... | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) | |||
3 | F, G, H, I, J... | BENZAMIDINE | non-polymer | 120.2 | 16 | Chemie (BEN) | |||
4 | E, H, P | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 16 - 245 (UniProt: P00760)
PDB | External Database | Details |
---|---|---|
Glu 97 | Asn 102 | engineered mutation |
Tyr 99 | Leu 104 | engineered mutation |
Ser 172 | Tyr 175 | engineered mutation |
Ser 173 | Pro 176 | engineered mutation |
Phe 174 | Gly 177 | engineered mutation |
Ile 175 | Gln 178 | engineered mutation |
Val 183 | Ala 186 | engineered mutation |
Ala 190 | Ser 195 | engineered mutation |
Glu 217 | Ser 218 | engineered mutation |
Phe 227 | Val 228 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 16 |
Total formula weight | 375687.5 | |
Non-Polymers* | Number of molecules | 35 |
Total formula weight | 2670.0 | |
All* | Total formula weight | 378357.5 |