3UXU
The structure of the catalytic domain of the Sulfolobus Spindle-shaped viral integrase reveals an evolutionarily conserved catalytic core and supports a mechanism of DNA cleavage in trans
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Probable integrase | polymer | 169 | 20021.2 | 1 | UniProt (P20214) Pfam (PF16795) | Sulfolobus virus 1 | |
2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
3 | C (A) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 173 - 335 (UniProt: P20214)
PDB | External Database | Details |
---|---|---|
Val 215 | Ile 215 | engineered mutation |
Ala 307 | Thr 307 | engineered mutation |
His 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
His 341 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 20021.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 95.0 | |
All* | Total formula weight | 20116.2 |