3UXP
Co-crystal Structure of Rat DNA polymerase beta Mutator I260Q: Enzyme-DNA-ddTTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA polymerase beta | polymer | 335 | 38403.7 | 2 | UniProt (P06766) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Rattus norvegicus (rat) | |
| 2 | C, E (P, D) | DNA 5'-D(P*AP*TP*GP*TP*GP*AP*G)-3' | polymer | 7 | 2177.5 | 2 | |||
| 3 | D, F (T, E) | DNA 5'-D(P*AP*CP*TP*CP*AP*CP*AP*TP*A)-3' | polymer | 9 | 2683.8 | 2 | |||
| 4 | G, L (A, B) | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 466.2 | 2 | Chemie (D3T) | |||
| 5 | H, I, J, K, M... (A, B) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) | |||
| 6 | P, Q, R, S, T... (A, B, P, T, D...) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 335 (UniProt: P06766)
| PDB | External Database | Details |
|---|---|---|
| Gln 260 | Ile 260 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 86530.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1093.3 | |
| All* | Total formula weight | 87623.3 |
