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3UVY

Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ABromodomain-containing protein 4polymer12715099.41UniProt (O60885)
Pfam (PF00439)
In PDB
Homo sapiens (human)Protein HUNK1
2BHistone H4polymer111480.71UniProt (P62805)
In PDB
Homo sapiensPeptide (H4K16acK20ac)
3waterwater18.065Chemie (HOH)
Sequence modifications
A: 44 - 168 (UniProt: O60885)
PDBExternal DatabaseDetails
Ser 42-expression tag
Met 43-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight16580.1
All*Total formula weight16580.1
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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