3UU1
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS142)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Anthranilate phosphoribosyltransferase | polymer | 377 | 38717.7 | 4 | UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5) In PDB | Mycobacterium tuberculosis | |
2 | A, B, C, D | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 4 | Chemie (PRP) | |||
3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
4 | A, B, C, D | 2-amino-3,5-dimethylbenzoic acid | non-polymer | 165.2 | 6 | Chemie (14B) | |||
5 | water | water | 18.0 | 1087 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 370 (UniProt: P66992)
PDB | External Database | Details |
---|---|---|
Leu 371 | - | expression tag |
Glu 372 | - | expression tag |
His 373 | - | expression tag |
His 374 | - | expression tag |
His 375 | - | expression tag |
His 376 | - | expression tag |
His 377 | - | expression tag |
His 378 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 154870.8 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2745.9 | |
All* | Total formula weight | 157616.6 |