3US9

Crystal Structure of the NCX1 Intracellular Tandem Calcium Binding Domains(CBD12)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Sodium/calcium exchanger 1	polymer	295	32978.4	1	UniProt (P23685) Pfam (PF03160)	Canis lupus familiaris (dogs)	Na(+)/Ca(2+)-exchange protein 1
2	B, C, D (A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
3	E (A)	water	water		18.0	12	Chemie (HOH)

Sequence modifications

A: 371 - 603 (UniProt: P23685)

PDB	External Database	Details
Met 363	-	expression tag
Ser 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
Lys 454	Glu 486	engineered mutation

A: 604 - 609 (UniProt: P23685)
A: 610 - 657 (UniProt: P23685)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	32978.4
Non-Polymers*	Number of molecules	3
	Total formula weight	120.2
All*	Total formula weight	33098.7

*Water molecules are not included.