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3US1

Structure of p63 DNA Binding Domain in Complex with a 22 Base Pair Response Element Containing a Two Base Pair "GC" Spacer Between Half Sites

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, D)
Tumor protein 63polymer20322683.92UniProt (Q9H3D4)
Pfam (PF00870)
Homo sapiens (human)TP63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, Tumor protein p73-like, p73L, p40, p51
2C
(F)
5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*GP*CP*AP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3'polymer226749.41
3D, E
(A, D)
ZINC IONnon-polymer65.42Chemie (ZN)
4F, G, H
(A, D, F)
waterwater18.0174Chemie (HOH)
Sequence modifications
A, D: 127 - 323 (UniProt: Q9H3D4)
PDBExternal DatabaseDetails
Gly 121-expression tag
Ser 122-expression tag
His 123-expression tag
Met 124-expression tag
Ala 125-expression tag
Ser 126-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight52117.1
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight52247.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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