3US0

Structure of p63 DNA Binding Domain in Complex with a 22 Base Pair A/T Rich Response Element Containing a Two Base Pair "AT" Spacer Between Half Sites

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Tumor protein 63	polymer	203	22683.9	4	UniProt (Q9H3D4) Pfam (PF00870) In PDB	Homo sapiens (human)	TP63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, Tumor protein p73-like, p73L, p40, p51
2	E, F	5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3'	polymer	22	6748.4	2
3	A, B, C, D	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4		water	water		18.0	394	Chemie (HOH)

Sequence modifications

A, B, C, D: 127 - 323 (UniProt: Q9H3D4)

PDB	External Database	Details
Gly 121	-	expression tag
Ser 122	-	expression tag
His 123	-	expression tag
Met 124	-	expression tag
Ala 125	-	expression tag
Ser 126	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	104232.3
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	104493.9

*Water molecules are not included.