3URF

Human RANKL/OPG complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tumor necrosis factor ligand superfamily member 11, soluble form	polymer	162	18424.5	1	UniProt (O14788) Pfam (PF00229)	Homo sapiens (human)	Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE
2	B (Z)	Tumor necrosis factor receptor superfamily member 11B	polymer	171	19737.3	1	UniProt (O00300) Pfam (PF00020)	Homo sapiens (human)	Osteoclastogenesis inhibitory factor, Osteoprotegerin
3	C (Z)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	D, E (A, Z)	water	water		18.0	36	Chemie (HOH)

Sequence modifications

A: 162 - 317 (UniProt: O14788)

PDB	External Database	Details
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag

Z: 1 - 165 (UniProt: O00300)

PDB	External Database	Details
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38161.9
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	38383.1

*Water molecules are not included.