3UQA
Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation A54E from Burkholderia pseudomallei complexed with FK506
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin-like protein SMT3, Peptidyl-prolyl cis-trans isomerase | polymer | 209 | 23059.9 | 1 | UniProt (Q12306) UniProt (Q3JK38) Pfam (PF00240) Pfam (PF00254) UniProt (by SIFTS) (Q63J95) | Saccharomyces cerevisiae (Baker's yeast) | |
| 2 | B (A) | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | non-polymer | 804.0 | 1 | Chemie (FK5) PubChem (23377000) PubChem (177746942) PubChem (23308325) PubChem (23581796) PubChem (24978521) PubChem (44294761) PubChem (44314852) PubChem (44575549) PubChem (46783859) PubChem (46781577) PubChem (49874294) PubChem (54611630) PubChem (57417278) PubChem (57892354) PubChem (57910335) PubChem (58584114) PubChem (59032416) PubChem (58946030) PubChem (59141120) PubChem (59049316) PubChem (59974193) PubChem (59993548) PubChem (60035606) PubChem (66709866) PubChem (67340654) PubChem (67626881) PubChem (68219140) PubChem (68712665) PubChem (69247758) PubChem (176478128) PubChem (176856280) PubChem (177675132) PubChem (5372) PubChem (57206900) PubChem (64779) PubChem (445643) PubChem (77906388) PubChem (89249909) PubChem (89545901) PubChem (89960652) PubChem (59042420) PubChem (59111253) PubChem (59112447) PubChem (59118415) PubChem (145857191) PubChem (59746606) PubChem (117646237) PubChem (6426916) PubChem (6436007) PubChem (6473866) PubChem (59917266) PubChem (59918741) PubChem (60086106) PubChem (66509027) PubChem (66672804) PubChem (123552884) PubChem (9832283) PubChem (9853905) PubChem (125039862) PubChem (9918805) PubChem (125136698) PubChem (125136697) PubChem (9963169) PubChem (129009965) PubChem (129010422) PubChem (130330191) PubChem (131676819) PubChem (133562888) PubChem (133688365) PubChem (11556866) PubChem (134694629) PubChem (71296869) PubChem (71316759) PubChem (71668407) PubChem (73265325) PubChem (12134936) PubChem (13006299) PubChem (137705868) PubChem (138106951) PubChem (138574020) PubChem (89068341) PubChem (140494820) PubChem (13819070) PubChem (140647114) PubChem (13819074) PubChem (13819069) PubChem (140893615) PubChem (149048732) PubChem (403209) PubChem (439492) PubChem (160433486) PubChem (162711219) PubChem (163027397) PubChem (163027399) PubChem (163027400) PubChem (166023667) PubChem (168312998) PubChem (170277719) PubChem (171042252) PubChem (171360199) PubChem (172042935) PubChem (173882479) PubChem (124511204) PubChem (5353987) PubChem (5472317) PubChem (125039860) PubChem (125039861) PubChem (125136699) PubChem (125136700) PubChem (125182986) PubChem (126687738) PubChem (6536850) PubChem (6610362) PubChem (129606865) PubChem (6912836) PubChem (131668141) PubChem (9940643) PubChem (137546410) PubChem (137546581) PubChem (138574025) PubChem (139032034) PubChem (140652196) PubChem (143265740) PubChem (144640477) PubChem (146323807) PubChem (13819073) PubChem (156417380) PubChem (156528350) PubChem (160433487) PubChem (163027398) PubChem (163027401) PubChem (163027402) PubChem (167413568) PubChem (170997009) PubChem (171122179) PubChem (171137683) PubChem (171156312) PubChem (171322980) PubChem (171329370) PubChem (172634670) PubChem (175667550) | |||
| 3 | C (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | E (A) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A: -85 - 0 (UniProt: Q12306)
A: 2 - 113 (UniProt: Q3JK38)
| PDB | External Database | Details |
|---|---|---|
| Met -95 | - | expression tag |
| Gly -94 | - | expression tag |
| His -93 | - | expression tag |
| His -92 | - | expression tag |
| His -91 | - | expression tag |
| His -90 | - | expression tag |
| His -89 | - | expression tag |
| His -88 | - | expression tag |
| Ser -87 | - | expression tag |
| Gly -86 | - | expression tag |
| Ser 1 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Glu 54 | Ala 54 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23059.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 945.6 | |
| All* | Total formula weight | 24005.5 |
