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3UOB

Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-deoxy-2'-beta-fluoro-cytidine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(C)
5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3'polymer237121.61
2B
(D)
5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1FC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3'polymer237063.51
3C, D
(A, B)
G/T mismatch-specific thymine DNA glycosylasepolymer20122771.32UniProt (Q13569)
Pfam (PF03167)
Homo sapiens (human)Thymine-DNA glycosylase, TDG
Sequence modifications
A, B: 111 - 308 (UniProt: Q13569)
PDBExternal DatabaseDetails
Ser 108-expression tag
Asn 109-expression tag
Ala 110-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight59727.7
All*Total formula weight59727.7
*Water molecules are not included.

248636

PDB entries from 2026-02-04

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