3UOB

Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-deoxy-2'-beta-fluoro-cytidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3'	polymer	23	7121.6	1
2	D	5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(1FC)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3'	polymer	23	7063.5	1
3	A, B	G/T mismatch-specific thymine DNA glycosylase	polymer	201	22771.3	2	UniProt (Q13569) Pfam (PF03167) In PDB	Homo sapiens (human)	Thymine-DNA glycosylase, TDG

Sequence modifications

A, B: 111 - 308 (UniProt: Q13569)

PDB	External Database	Details
Ser 108	-	expression tag
Asn 109	-	expression tag
Ala 110	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	59727.7
All*	Total formula weight	59727.7

*Water molecules are not included.