3UO5
Aurora A in complex with YL1-038-31
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/Threonine-Protein Kinase 6 | polymer | 279 | 32359.1 | 1 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (human) | aurora-A kinase, Serine/threonine kinase 15, Aurora/IPL1-related kinase 1, Surora-related kinase 1, hARK1, Surora-A, Breast-tumor-amplified kinase; |
| 2 | B (A) | 4-{[4-(phenylamino)pyrimidin-2-yl]amino}benzoic acid | non-polymer | 306.3 | 1 | Chemie (0BX) | |||
| 3 | C (A) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 123 - 401 (UniProt: O14965)
| PDB | External Database | Details |
|---|---|---|
| Asp 287 | Thr 287 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32359.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 306.3 | |
| All* | Total formula weight | 32665.4 |
