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3UMR

Crystal structure of the G202D mutant of human G-alpha-i1

Replaces:  2EBC
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440390.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E, F
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
5G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
6H
(A)
waterwater18.0215Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Asp 202Gly 202engineered mutation
Cys 258Trp 258conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40390.0
Non-Polymers*Number of molecules6
Total formula weight737.7
All*Total formula weight41127.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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