3UMK
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with copper
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Amyloid beta A4 protein | polymer | 211 | 25062.4 | 1 | UniProt (P05067) Pfam (PF12925) In PDB | Homo sapiens (human) | |
| 2 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 3 | A | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 4 | A | CADMIUM ION | non-polymer | 112.4 | 7 | Chemie (CD) | |||
| 5 | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A: 295 - 500 (UniProt: P05067)
| PDB | External Database | Details |
|---|---|---|
| Met 294 | - | initiating methionine |
| Ile 501 | - | expression tag |
| Glu 502 | - | expression tag |
| Gly 503 | - | expression tag |
| Arg 504 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25062.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 973.0 | |
| All* | Total formula weight | 26035.4 |
