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3UL7

Crystal structure of the TV3 mutant F63W

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Toll-like receptor 4, Variable lymphocyte receptor Bpolymer27831296.91UniProt (O00206)
UniProt (Q4G1L2)
Pfam (PF13855)
Pfam (PF12799)
Pfam (PF11921)
Homo sapiens (human Inshore hagfish)hToll
2B
(B)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G15407YE)
3C
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
4D
(A)
beta-L-fucopyranosenon-polymer164.21Chemie (FUL)
5E, F, G
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
6H
(A)
waterwater18.050Chemie (HOH)
Sequence modifications
A: 28 - 228 (UniProt: O00206)
PDBExternal DatabaseDetails
Gly 26-expression tag
Ser 27-expression tag
Trp 63Phe 63engineered mutation
A: 229 - 302 (UniProt: Q4G1L2)
PDBExternal DatabaseDetails
Arg 227-expression tag
Leu 228-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31296.9
BranchedNumber of molecules1
Total formula weight586.5
Non-Polymers*Number of molecules5
Total formula weight673.6
All*Total formula weight32557.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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