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3UGL

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BProteine kinase C delta typepolymer657376.62UniProt (P28867)
Pfam (PF00130)
In PDB
Mus musculus (mouse)nPKC-delta
2A, BZINC IONnon-polymer65.44Chemie (ZN)
3A, Bcyclopropylmethanolnon-polymer72.12Chemie (09V)
4A, BPHOSPHATE IONnon-polymer95.03Chemie (PO4)
5waterwater18.0211Chemie (HOH)
Sequence modifications
A, B: 231 - 280 (UniProt: P28867)
PDBExternal DatabaseDetails
Gly 222-expression tag
Ser 223-expression tag
Arg 224-expression tag
Arg 225-expression tag
Ala 226-expression tag
Ser 227-expression tag
Val 228-expression tag
Gly 229-expression tag
Ser 230-expression tag
Glu 281-expression tag
Phe 282-expression tag
Ile 283-expression tag
Val 284-expression tag
Thr 285-expression tag
Asp 286-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight14753.1
Non-Polymers*Number of molecules9
Total formula weight690.8
All*Total formula weight15443.9
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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