3UGI

Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase C delta

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein kinase C delta type	polymer	65	7376.6	2	UniProt (P28867) Pfam (PF00130)	Mus musculus (mouse)	nPKC-delta
2	C, D, H, I (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	E, J (A, B)	(methoxymethyl)cyclopropane	non-polymer		86.1	2	Chemie (09U)
4	F, G, K, L, M... (A, B)	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
5	O, P (A, B)	water	water		18.0	196	Chemie (HOH)

Sequence modifications

A, B: 231 - 280 (UniProt: P28867)

PDB	External Database	Details
Gly 222	-	expression tag
Ser 223	-	expression tag
Arg 224	-	expression tag
Arg 225	-	expression tag
Ala 226	-	expression tag
Ser 227	-	expression tag
Val 228	-	expression tag
Gly 229	-	expression tag
Ser 230	-	expression tag
Glu 281	-	expression tag
Phe 282	-	expression tag
Ile 283	-	expression tag
Val 284	-	expression tag
Thr 285	-	expression tag
Asp 286	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	14753.1
Non-Polymers*	Number of molecules	12
	Total formula weight	1003.7
All*	Total formula weight	15756.8

*Water molecules are not included.