3UDD
Tankyrase-1 in complex with small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tankyrase-1 | polymer | 224 | 25409.7 | 2 | UniProt (O95271) Pfam (PF00644) In PDB | Homo sapiens (human) | TANK1, Poly [ADP-ribose] polymerase 5A, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | 3-(4-methoxyphenyl)-5-({[4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,2,4-oxadiazole | non-polymer | 409.5 | 2 | Chemie (34M) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A, B: 1105 - 1327 (UniProt: O95271)
| PDB | External Database | Details |
|---|---|---|
| Gly 1104 | - | expression tag |
| Ile 1266 | Met 1266 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50819.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1894.5 | |
| All* | Total formula weight | 52713.9 |
