3UD5
Crystal structure of E. coli HPPK in complex with bisubstrate analogue inhibitor J1A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | polymer | 158 | 17966.5 | 1 | UniProt (P26281) Pfam (PF01288) | Escherichia coli | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK |
| 2 | B (A) | 5'-S-[1-(2-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}ethyl)piperidin-4-yl]-5'-thioadenosine | non-polymer | 584.7 | 1 | Chemie (J1A) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17966.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 708.8 | |
| All* | Total formula weight | 18675.3 |
