3UBX

Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Antigen-presenting glycoprotein CD1d1	polymer	286	32770.8	2	UniProt (P11609) Pfam (PF16497) Pfam (PF07654) In PDB	Mus musculus (mouse)	T cell surface glycoprotein CD1d
2	B, E	Beta-2-microglobulin	polymer	99	11660.4	2	UniProt (P01887) Pfam (PF07654) In PDB	Mus musculus (mouse)
3	L, I	L363 light chain (IGKV13-84*01)	polymer	214	23594.0	2		Mus musculus (mouse)
4	H, G	L363 heavy chain (IGHV9-4*02)	polymer	222	23884.9	2		Mus musculus (mouse)
5	C, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
6	A, D	(11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide	non-polymer		770.1	2	Chemie (09N)
7	A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, D: 1 - 279 (UniProt: P11609)

PDB	External Database	Details
His 201	Asp 219	SEE REMARK 999
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag
His 286	-	expression tag

B, E: 1 - 99 (UniProt: P01887)

PDB	External Database	Details
Ala 85	Asp 105	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	183820.0
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1982.7
All*	Total formula weight	186651.5

*Water molecules are not included.