3UBE

Influenza hemagglutinin from the 2009 pandemic in complex with ligand LSTc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	Hemagglutinin HA1	polymer	329	36535.3	6	UniProt (C3W5S1) Pfam (PF00509) In PDB	Influenza A virus
2	B, D, F, H, J...	Hemagglutinin HA2	polymer	177	20278.4	6	UniProt (C3W5S1) Pfam (PF00509) In PDB	Influenza a virus
3	M, N, R	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose	branched		836.7	3	In PDB GlyTouCan (G03509EL)
4	O, Q	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	2	In PDB BIRD (PRD_900046) GlyTouCan (G73578JC)		6'-sialyl-N-acetyllactosamine
5	P	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	A, C, E, J, K	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)
7	G	N-acetyl-alpha-neuraminic acid	non-polymer		309.3	1	Chemie (SIA)
8		water	water		18.0	878	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 11 - 329 (UniProt: C3W5S1)

PDB	External Database	Details
Pro 9	-	expression tag
Gly 10	-	expression tag
Cys 205	Gly 219	engineered mutation
Cys 220	Arg 234	engineered mutation

B, D, F, H, J, L: 1 - 174 (UniProt: C3W5S1)

PDB	External Database	Details
Ser 175	-	expression tag
Gly 176	-	expression tag
Arg 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	340882.0
Branched	Number of molecules	6
	Total formula weight	4283.8
Non-Polymers*	Number of molecules	8
	Total formula weight	1857.7
All*	Total formula weight	347023.6

*Water molecules are not included.