3UA7
Crystal Structure of the Human Fyn SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tyrosine-protein kinase Fyn | polymer | 64 | 7171.8 | 4 | UniProt (P06241) Pfam (PF00018) | Homo sapiens (human) | Proto-oncogene Syn, Proto-oncogene c-Fyn, Src-like kinase, SLK, p59-Fyn |
| 2 | E, F (E, F) | Non-structural protein 5A | polymer | 12 | 1314.6 | 2 | UniProt (Q9YKI6) UniProt (by SIFTS) (P26663) | Hepatitis C virus | NS5A |
| 3 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | J, L (C, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | K, M (C, D) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 8 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 81 - 143 (UniProt: P06241)
E, F: 1 - 11 (UniProt: Q9YKI6)
| PDB | External Database | Details |
|---|---|---|
| Met 80 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 31316.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 373.4 | |
| All* | Total formula weight | 31689.7 |
