3U9U
Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of mAb1479
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Fab Heavy Chain | polymer | 224 | 24195.1 | 2 | Mus musculus (mouse) | ||
| 2 | B, D | Fab Light Chain | polymer | 219 | 24205.8 | 2 | Mus musculus (mouse) | ||
| 3 | E, F | Receptor tyrosine-protein kinase erbB-4 | polymer | 625 | 69867.8 | 2 | UniProt (Q15303) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) In PDB | Homo sapiens (human) | Proto-oncogene-like protein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4, p180erbB4, ERBB4 intracellular domain, 4ICD, E4ICD, s80HER4 |
Sequence modifications
E, F: 1 - 625 (UniProt: Q15303)
| PDB | External Database | Details |
|---|---|---|
| Asp 524 | Gly 549 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 236537.4 | |
| All* | Total formula weight | 236537.4 |
