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3U8T

Human thrombin complexed with D-Phe-Pro-D-Arg-Cys

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
Thrombin light chainpolymer273188.61UniProt (P00734)
Pfam (PF09396)
Homo sapiens (human)Prothrombin
2B
(H)
Thrombin heavy chainpolymer25929780.21UniProt (P00734)
Pfam (PF00089)
Homo sapiens (human)Prothrombin
3C
(I)
D-PHE-PRO-D-ARG-CYS DIRECT THROMBIN INHIBITORpolymer5520.61BIRD (PRD_001092)
4D
(H)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
5E
(H)
SODIUM IONnon-polymer23.01Chemie (NA)
6F
(H)
IODIDE IONnon-polymer126.91Chemie (IOD)
7G
(H)
CHLORIDE IONnon-polymer35.51Chemie (CL)
8H
(H)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
9I, J, K
(L, H, I)
waterwater18.0265Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight33489.5
Non-Polymers*Number of molecules5
Total formula weight524.7
All*Total formula weight34014.2
*Water molecules are not included.

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PDB entries from 2025-12-24

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