3U7K
Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptide deformylase | polymer | 191 | 21692.7 | 1 | UniProt (Q5HGZ3) Pfam (PF01327) | Staphylococcus aureus | PDF, Polypeptide deformylase |
| 2 | B (A) | (S)-N-(cyclopentylmethyl)-N-(2-(hydroxyamino)-2-oxoethyl)-2-(3-(2-methoxyphenyl)ureido)-3,3-dimethylbutanamide | non-polymer | 434.5 | 1 | Chemie (MDB) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
A: 1 - 183 (UniProt: Q5HGZ3)
| PDB | External Database | Details |
|---|---|---|
| Leu 184 | - | expression tag |
| Glu 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21692.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 499.9 | |
| All* | Total formula weight | 22192.7 |
