3U7G
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bifunctional polynucleotide phosphatase/kinase | polymer | 379 | 42188.5 | 1 | UniProt (Q9JLV6) Pfam (PF08645) Pfam (PF13671) | Mus musculus (mouse) | DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase, Polynucleotide 3'-phosphatase, 2'(3')-polynucleotidase, Polynucleotide 5'-hydroxyl-kinase |
| 2 | B (X) | DNA | polymer | 5 | 1455.0 | 1 | |||
| 3 | C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F, H (A, X) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | I, J (A, X) | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A: 144 - 522 (UniProt: Q9JLV6)
| PDB | External Database | Details |
|---|---|---|
| Ala 170 | Asp 170 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43643.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 490.5 | |
| All* | Total formula weight | 44134.1 |
