3U74
Crystal structure of stabilized human uPAR mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | U | Urokinase plasminogen activator surface receptor | polymer | 283 | 31455.4 | 1 | UniProt (Q03405) Pfam (PF00021) In PDB | Homo sapiens (human) | U-PAR, uPAR, Monocyte activation antigen Mo3 |
| 2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | U | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
U: 1 - 283 (UniProt: Q03405)
| PDB | External Database | Details |
|---|---|---|
| Cys 47 | His 69 | engineered mutation |
| Cys 259 | Asn 281 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31455.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 32101.0 |
