3U3Z
Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Microcephalin | polymer | 199 | 21949.6 | 1 | UniProt (Q8NEM0) | Homo sapiens (human) | |
| 2 | B (B) | Histone H2A.X peptide | polymer | 4 | 685.5 | 1 | UniProt (by SIFTS) (P16104) | Homo sapiens | |
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A: 640 - 835 (UniProt: Q8NEM0)
| PDB | External Database | Details |
|---|---|---|
| Gly 637 | - | expression tag |
| His 638 | - | expression tag |
| Met 639 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22635.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 22819.2 |






