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3U3D

Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transcriptional regulatory protein sir2 homologuepolymer29032050.21UniProt (Q8IE47)
Pfam (PF02146)
Plasmodium falciparumSir2A
2B
(B)
histone 3 myristoyl lysine 9 peptidepolymer121617.91UniProt (by SIFTS) (P68431)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5E
(A)
waterwater18.025Chemie (HOH)
Sequence modifications
A: 1 - 273 (UniProt: Q8IE47)
PDBExternal DatabaseDetails
Gly -16-expression tag
Ser -15-expression tag
His -14-expression tag
Met -13-expression tag
Ala -12-expression tag
Ser -11-expression tag
Met -10-expression tag
Thr -9-expression tag
Gly -8-expression tag
Gly -7-expression tag
Gln -6-expression tag
Gln -5-expression tag
Met -4-expression tag
Gly -3-expression tag
Arg -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight33668.2
Non-Polymers*Number of molecules2
Total formula weight157.5
All*Total formula weight33825.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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