3U12

The pleckstrin homology (PH) domain of USP37

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	USP37 protein	polymer	141	15840.5	2	UniProt (Q86W68) Pfam (PF16674) UniProt (by SIFTS) (Q86T82)	Homo sapiens (human)	Uncharacterized protein
2	C, D, DA, E (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	EA, F (B, A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	AA, FA, G, GA, H... (A, B)	UNKNOWN ATOM OR ION	non-polymer			29	Chemie (UNX)
5	BA, CA (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	NA, OA (A, B)	water	water		18.0	85	Chemie (HOH)

Sequence modifications

A, B: 4 - 125 (UniProt: Q86W68)

PDB	External Database	Details
Mse -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Leu -2	-	expression tag
Val -1	-	expression tag
Pro 0	-	expression tag
Arg 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31680.9
Non-Polymers*	Number of molecules	37
	Total formula weight	626.5
All*	Total formula weight	32307.4

*Water molecules are not included.