3U10
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | polymer | 210 | 24531.1 | 1 | UniProt (Q9UL51) Pfam (PF00027) | Homo sapiens (human) | Brain cyclic nucleotide-gated channel 2, BCNG-2 |
| 2 | B (A) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 1 | Chemie (CMP) PubChem (23902375) PubChem (25322948) PubChem (40467852) PubChem (44629928) PubChem (176488666) PubChem (25322946) PubChem (59350541) PubChem (274) PubChem (56973690) PubChem (59909322) PubChem (59968988) PubChem (6604194) PubChem (70878457) PubChem (6076) PubChem (216878) PubChem (163043517) PubChem (3080770) PubChem (3246347) PubChem (124132380) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (129317551) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (12071879) PubChem (12866365) PubChem (163043518) | |||
| 3 | C (A) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 470 - 672 (UniProt: Q9UL51)
| PDB | External Database | Details |
|---|---|---|
| Gln 463 | - | expression tag |
| Gly 464 | - | expression tag |
| Pro 465 | - | expression tag |
| Ser 466 | - | expression tag |
| Ser 467 | - | expression tag |
| Pro 468 | - | expression tag |
| Met 469 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24531.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 329.2 | |
| All* | Total formula weight | 24860.3 |
