3U10
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | polymer | 210 | 24531.1 | 1 | UniProt (Q9UL51) Pfam (PF00027) | Homo sapiens (human) | Brain cyclic nucleotide-gated channel 2, BCNG-2 |
| 2 | B (A) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 1 | Chemie (CMP) | |||
| 3 | C (A) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 470 - 672 (UniProt: Q9UL51)
| PDB | External Database | Details |
|---|---|---|
| Gln 463 | - | expression tag |
| Gly 464 | - | expression tag |
| Pro 465 | - | expression tag |
| Ser 466 | - | expression tag |
| Ser 467 | - | expression tag |
| Pro 468 | - | expression tag |
| Met 469 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24531.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 329.2 | |
| All* | Total formula weight | 24860.3 |
