3TZY
Crystal structure of a fragment containing the acyltransferase domain of Pks13 from Mycobacterium tuberculosis in the palmitoylated form at 2.2 A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Polyketide synthase PKS13 | polymer | 491 | 53086.8 | 2 | UniProt (O53579) Pfam (PF00698) | Mycobacterium tuberculosis | Polyketide synthase |
| 2 | C, D (C, D) | 12-mer peptide | polymer | 12 | 1355.5 | 2 | Escherichia coli | Co-crystallized peptide | |
| 3 | E, K (A, B) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 4 | F, G, H, I, J... (A, B) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 5 | N, O (B, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | P, Q, R (A, B, D) | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A, B: 576 - 1062 (UniProt: O53579)
| PDB | External Database | Details |
|---|---|---|
| Gly 572 | - | expression tag |
| Ser 573 | - | expression tag |
| His 574 | - | expression tag |
| Met 575 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 108884.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1349.6 | |
| All* | Total formula weight | 110234.2 |
