3TZM
TGF-beta Receptor type 1 in complex with SB431542
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TGF-beta receptor type-1 | polymer | 309 | 35228.6 | 1 | UniProt (P36897) Pfam (PF00069) In PDB | Homo sapiens (human) | TGFR-1, Activin A receptor type II-like protein kinase of 53kD, Activin receptor-like kinase 5, ALK-5, ALK5, Serine/threonine-protein kinase receptor R4, SKR4, TGF-beta type I receptor, Transforming growth factor-beta receptor type I, TGF-beta receptor type I, TbetaR-I |
| 2 | A | 4-[5-(1,3-benzodioxol-5-yl)-4-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide | non-polymer | 384.4 | 1 | Chemie (085) | |||
| 3 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 200 - 503 (UniProt: P36897)
| PDB | External Database | Details |
|---|---|---|
| Gly 195 | - | expression tag |
| Ala 196 | - | expression tag |
| Met 197 | - | expression tag |
| Gly 198 | - | expression tag |
| Ser 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35228.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 35612.9 |
