3TZ0

Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial	polymer	418	47374.2	1	UniProt (Q00972) Pfam (PF10436) Pfam (PF02518)	Rattus norvegicus (rat)	Branched-chain alpha-ketoacid dehydrogenase kinase, BCKD-kinase, BCKDHKIN
2	B (A)	(2S)-2-chloro-4-methylpentanoic acid	non-polymer		150.6	1	Chemie (03H)
3	C (A)	water	water		18.0	21	Chemie (HOH)

Sequence modifications

A: -29 - 382 (UniProt: Q00972)

PDB	External Database	Details
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag
His 388	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	47374.2
Non-Polymers*	Number of molecules	1
	Total formula weight	150.6
All*	Total formula weight	47524.8

*Water molecules are not included.