3TWX
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tankyrase-2 | polymer | 165 | 17851.2 | 2 | UniProt (Q9H2K2) Pfam (PF12796) | Homo sapiens (human) | TANK2, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein |
| 2 | C, D (C, D) | human FNBP1 | polymer | 16 | 1856.0 | 2 | Homo sapiens | ||
| 3 | E (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 4 | F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | H, I, J, K, L (B, C, D) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A, B: 488 - 649 (UniProt: Q9H2K2)
| PDB | External Database | Details |
|---|---|---|
| Gly 485 | - | expression tag |
| Ala 486 | - | expression tag |
| Met 487 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 39414.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 886.8 | |
| All* | Total formula weight | 40301.2 |
