3TWV
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human NUMA1 (chimeric peptide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tankyrase-2 | polymer | 165 | 17851.2 | 4 | UniProt (Q9H2K2) Pfam (PF12796) | Homo sapiens (human) | TANK2, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein |
| 2 | E, F, G, H (E, F, G, H) | human NUMA1 | polymer | 16 | 1869.1 | 4 | Homo sapiens | ||
| 3 | I, M, N (A, C) | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | non-polymer | 370.4 | 3 | Chemie (PE8) | |||
| 4 | J, P, S, T, U... (A, C, D, F, G...) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 5 | K, L, O, Q, R... (B, C, D, G) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 488 - 649 (UniProt: Q9H2K2)
| PDB | External Database | Details |
|---|---|---|
| Gly 485 | - | expression tag |
| Ala 486 | - | expression tag |
| Met 487 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 78881.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2156.2 | |
| All* | Total formula weight | 81037.2 |
