3TWT
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 (chimeric peptide)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Tankyrase-2 | polymer | 165 | 17851.2 | 4 | UniProt (Q9H2K2) Pfam (PF12796) In PDB | Homo sapiens (human) | TANK2, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein |
2 | E, F, G, H | human MCL1 | polymer | 16 | 1832.1 | 4 | Homo sapiens | ||
3 | A | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 1 | Chemie (2PE) | |||
4 | A, B, C, D, E | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
5 | A, B, D, F | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
6 | C | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL | non-polymer | 370.4 | 2 | Chemie (PE8) | |||
7 | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 488 - 649 (UniProt: Q9H2K2)
PDB | External Database | Details |
---|---|---|
Gly 485 | - | EXPRESSION TAG |
Ala 486 | - | EXPRESSION TAG |
Met 487 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 78733.3 | |
Non-Polymers* | Number of molecules | 17 |
Total formula weight | 2160.3 | |
All* | Total formula weight | 80893.6 |