3TV3
Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with Man9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | PGT128 light chain, Ig lambda-2 chain C regions | polymer | 211 | 22223.6 | 1 | UniProt (P0CG05) Pfam (PF07654) UniProt (by SIFTS) (P0DOY2) | Homo sapiens (human) | |
| 2 | B (H) | PGT128 heavy chain, Ig gamma-1 chain C region | polymer | 239 | 25562.7 | 1 | UniProt (P01857) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (A) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose | branched | 1315.1 | 1 | In PDB GlyTouCan (G65997KL) | |||
| 4 | D, F, G, H (L, H) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | E (H) | AMYLAMINE | non-polymer | 87.2 | 1 | Chemie (AML) | |||
| 6 | I (H) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 7 | J, K (L, H) | water | water | 18.0 | 306 | Chemie (HOH) |
Sequence modifications
L: 1 - 106 (PDB: 3TV3)
L: 107 - 215 (UniProt: P0CG05)
H: 1 - 113 (PDB: 3TV3)
H: 114 - 231 (UniProt: P01857)
L: 107 - 215 (UniProt: P0CG05)
H: 1 - 113 (PDB: 3TV3)
H: 114 - 231 (UniProt: P01857)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47786.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1315.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 693.8 | |
| All* | Total formula weight | 49795.3 |
